Florinef Tablet 0.1mg – Fludrocortisone

Essential Hormone Replacement for Adrenal Insufficiency

What Is Fludrocortisone Acetate?

Fludrocortisone Acetate Tablets are a prescription corticosteroid medication used to treat conditions in which the body does not produce sufficient adrenal hormones. Commonly prescribed as a replacement therapy for Addison’s disease, adrenocortical insufficiency, and salt-losing adrenogenital syndrome, this medication plays a critical role in maintaining essential physiological balance.

Formerly available under the brand name Florinef, which has been discontinued in the United States, fludrocortisone acetate remains widely available in generic form and continues to be a trusted option in endocrine care.

How Fludrocortisone Acetate Works

Fludrocortisone acetate is a synthetic mineralocorticoid corticosteroid that replaces hormones normally produced by the adrenal glands. These hormones are vital for regulating salt and water balance, maintaining normal blood pressure, and supporting carbohydrate metabolism.

By restoring hormonal balance, fludrocortisone helps the body function properly when adrenal hormone production is insufficient due to disease or congenital conditions.

Indications and Therapeutic Uses

Fludrocortisone acetate is prescribed for the management of several adrenal disorders, including:

• Addison’s disease
• Adrenocortical insufficiency
• Salt-losing adrenogenital syndrome
• Other conditions associated with low glucocorticoid or mineralocorticoid levels

It is often used in combination with other medications, such as hydrocortisone, to provide comprehensive hormone replacement therapy tailored to the patient’s needs.

Dosage and Administration

Dosage is individualized based on disease severity and patient response. For Addison’s disease, the typical dose is 0.1 mg daily, while higher doses may be required for salt-losing conditions. Tablets are taken orally as prescribed by a healthcare professional.

Patients should follow their physician’s instructions closely and avoid altering the dose without medical guidance.

Safety, Precautions, and Monitoring

Fludrocortisone acetate should be used with caution during pregnancy and breastfeeding, as the medication can pass into breast milk and may affect a nursing infant. Regular medical supervision is essential, especially during long-term therapy.

Patients should inform their doctor of all medications, supplements, and underlying conditions to prevent potential drug interactions. Ongoing monitoring may be required to assess electrolyte balance, blood pressure, and overall treatment response.

Possible Side Effects

Like other corticosteroids, fludrocortisone may cause side effects ranging from mild to serious. These can include fluid retention, changes in blood pressure, muscle weakness, mood changes, gastrointestinal discomfort, and skin changes. Serious symptoms require immediate medical attention.

Storage and Handling

Store fludrocortisone acetate tablets at room temperature, away from moisture, heat, and direct light. Keep the medication out of reach of children and store it in its original packaging to maintain stability.

Important Medical Notice & Call to Action

Fludrocortisone Acetate is a prescription medication and must be used under the supervision of a qualified healthcare professional.

Consult your doctor today to determine whether fludrocortisone acetate is appropriate for your condition and to receive personalized dosing and monitoring for safe, effective adrenal hormone replacement therapy.